check integrity of SPP and SPS

after suspected activities (i think virus or malware or ransomware) in the network i need to know what check i can do in SPP and SPS to be sure that all the appliances are not been impacted.

is it possible to check if there are any dangerous files ?

Are there any best practice about it?

Are there any specific checks i can do it?

Are there any file that i can check if they are corrupted?

anything else i can do it to check all appliances (virtual and physical) and their total integrity?

many thanks!!!

and have a good holidays!