Question about Cloud Workload Support

Hi,

Does Safeguard supports and manage workloads which are hosted in the cloud? Assuming connectivity between on-prem SPP and managed workload is in place. Perhaps an example, would make sense, lets say we have a Windows Server 2019 VM (spin from the image library) resource deployed in Azure cloud and we have site to site VPN deployed between on prem datacenter and Azure network. Safeguard is able to ping and reach the server thru the ports required. Would Safeguard be able to manage such workload seemlessly? 

Reason of this question is, we are unsure if this is a supported platform as its a cloud resource. We understand that Safeguard does support Windows Server but that's might be a tricky situation since it's hosted in the cloud.