Specify Exchange Server


I'm wondering if anyone has ever setup an Exchange connection with a specified Exchange Server. I'm having trouble when doing this. I can connect to "Any available exchange Server in the forest.". Although when I specify a Exchange Server I get an error. 

I don't change anything but putting a Exchange server in place. I have a need to use this method for a sync job where we can only allow communication to a single server for this job.

Any help is appreciated. Lu